1062172-60-4
Chemical Structure
mTOR inhibitor WYE-28
- CAS No.: 1062172-60-4
- Formula:C30H34N8O5
- Molecular Weight:586.64
IUPAC Name: methyl 4-(6-(4-(3-(4-(hydroxymethyl)phenyl)ureido)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
InChIKey: DLIGFKRUAOAIBA-UHFFFAOYSA-N
SMILES: O=C(N1CCC(N2N=CC3=C(N=C(N=C32)C4=CC=C(C=C4)NC(NC5=CC=C(C=C5)CO)=O)N6CCOCC6)CC1)OC
Biological Activity: mTOR inhibitor WYE-28 (compound 28) is a selective inhibitor of mTOR (IC50 = 0.08 nM). mTOR inhibitor WYE-28 inhibits PI3Kα with an IC50 value of 6 nM. mTOR inhibitor WYE-28 shows a metabolic time (T1/2) in nude mouse microsomes of 13 min[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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mTOR inhibitor WYE-28 | 99.25% | mTOR inhibitor WYE-28 (compound 28) is a selective inhibitor of mTOR (IC50 = 0.08 nM). mTOR inhibitor WYE-28 inhibits PI3Kα with an IC50 value of 6 nM. mTOR inhibitor WYE-28 shows a metabolic time (T1/2) in nude mouse microsomes of 13 min. | ||||||||||||||||||||
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Keywords
