106519-34-0
Chemical Structure
Biotin-14-dATP
- CAS. Nr.: 106519-34-0
- Formula:C32H54N9O15P3S
- Molecular Weight:929.81
IUPAC Name: ((2R,3S,5R)-3-hydroxy-5-(6-((6-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)hexyl)amino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
InChIKey: USRXXRYCCJDJFL-QBQCUPHPSA-N
SMILES: O=C(N1)N[C@](CS2)([H])[C@@]1([H])[C@@H]2CCCCC(NCCCCCC(NCCCCCCNC3=NC=NC4=C3N=CN4[C@H]5C[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O5)=O)=O
Biological Activity: Biotin-14-dATP is a deoxyadenosine triphosphate analog modified by Biotin (HY-B0511), serving as a DNA labeling reagent that acts on E. coli DNA polymerase I. When incorporated into DNA probes, Biotin-14-dATP undergoes specific hybridization with complementary target DNA sequences, and its biotin group can bind to streptavidin-alkaline phosphatase conjugates, enabling colorimetric detection[1].
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Biotin-14-dATP | Biotin-14-dATP is a deoxyadenosine triphosphate analog modified by Biotin (HY-B0511), serving as a DNA labeling reagent that acts on E. coli DNA polymerase I. When incorporated into DNA probes, Biotin-14-dATP undergoes specific hybridization with complementary target DNA sequences, and its biotin group can bind to streptavidin-alkaline phosphatase conjugates, enabling colorimetric detection. | |||||||||||||||||||||
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