1065472-91-4
Chemical Structure
Hydroxy Bosentan-d4
Synonym(s): Ro 48-5033-d4
- CAS No.: 1065472-91-4
- Formula:C27H25D4N5O7S
- Molecular Weight:571.64
IUPAC Name: 4-(1-hydroxy-2-methylpropan-2-yl)-N-(6-(2-hydroxyethoxy-1,1,2,2-d4)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
InChIKey: FAJQMBCLPZWTQJ-ONNKGWAKSA-N
SMILES: COC1=CC=CC=C1OC2=C(OC([2H])([2H])C([2H])([2H])O)N=C(C3=NC=CC=N3)N=C2NS(C4=CC=C(C(C)(C)CO)C=C4)(=O)=O
Biological Activity: Hydroxy Bosentan-d4 is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].
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Hydroxy Bosentan-d4 | Hydroxy Bosentan-d4 is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities. | |||||||||||||||||||||
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Hydroxy Bosentan-d6 | Hydroxy Bosentan-d6 is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities. | |||||||||||||||||||||
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Hydroxy bosentan | Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities. | |||||||||||||||||||||
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