1066-17-7
Chemical Structure
Colistin
Synonym(s): Polymyxin E
- CAS No.: 1066-17-7
- Formula:N/A
- Molecular Weight:N/A
SMILES: [H][C@@]([C@@H](C)O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@@H](N1)CCN)=O)CC(C)C)=O)CC(C)C)=O)CCN)=O)CCN)=O)C(NCC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCC[R])=O)CCN)=O)[C@@H](C)O)=O)CCN)=O)C1=O)=O.[C]C(C)C.[C][C@H](CC)C.[R:].[R:].[Colistin B].[Colistin A]
Biological Activity: Colistin is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli[1][2].
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Colistin | 95% | Colistin is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli. | ||||||||||||||||||||
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References
- [1]. Silpak Biswas, et al. Colistin: an update on the antibiotic of the 21st century. Expert Rev Anti Infect Ther. 2012 Aug;10(8):917-34. [Content Brief]
- [2]. Jian Li, et al. Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate. [Content Brief]
