106854-46-0
106854-46-0
Chemical Structure
Argimesna ethanesulfonate
- CAS No.: 106854-46-0
- Formula:C8H20N4O5S2
- Molecular Weight:316.40
IUPAC Name: L-arginine compound with 2-mercaptoethane-1-sulfonic acid (1:1)
InChIKey: MZDDDSNBRVMDIH-WCCKRBBISA-N
SMILES: N[C@@H](CCCNC(N)=N)C(O)=O.SCCS(=O)(O)=O
Biological Activity: Argimesna ethanesulfonate is a uroprotective agent. Argimesna ethanesulfonate is promising for research of hemorrhagic cystitis in cancer chemotherapy[1][2].
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Argimesna ethanesulfonate | Argimesna ethanesulfonate is a uroprotective agent. Argimesna ethanesulfonate is promising for research of hemorrhagic cystitis in cancer chemotherapy. | |||||||||||||||||||||
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References
- [1]. Frustaci S, et al. Feasibility and efficacy of arginine 2-mercaptoethanesulfonate (ARGIMESNA) in the prevention of hemorragic cystitis from ifosfamide (IFO). Ann Oncol. 1992 Apr;3 Suppl 2:S115-8. [Content Brief]
- [2]. Miglioli P A, et al. A Comparative Analysis of the Urinary Excretion Profiles of Mesna and Argimesna Following Oral Administration to Healthy Volunteers[J]. Drug Investigation, 1992, 4(5): 391-394.
