107657-57-8
107657-57-8
Chemical Structure
(S)-Deoxy-thalidomide
- CAS No.: 107657-57-8
- Formula:C13H12N2O3
- Molecular Weight:244.25
InChIKey: WENKGSGGXGQHSH-JTQLQIEISA-N
SMILES: O=C(CC1)NC([C@H]1N2C(C3=CC=CC=C3C2)=O)=O
Biological Activity: (S)-Deoxy-thalidomide is an E3 ubiquitin ligase ligand. (S)-Deoxy-thalidomide can be linked to the target protein ligand through a linker to form PROTAC K-Ras Degrader-3 (HY-168054). PROTAC K-Ras Degrader-3 can target KRAS mutant proteins for degradation[1].
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(S)-Deoxy-thalidomide | (S)-Deoxy-thalidomide is an E3 ubiquitin ligase ligand. (S)-Deoxy-thalidomide can be linked to the target protein ligand through a linker to form PROTAC K-Ras Degrader-3 (HY-168054). PROTAC K-Ras Degrader-3 can target KRAS mutant proteins for degradation. | |||||||||||||||||||||
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References
Keywords
