108605-51-2
Chemical Structure
Deoxyenterocin
- CAS No.: 108605-51-2
- Formula:C22H20O9
- Molecular Weight:428.39
IUPAC Name: (3S,4aR,5S,6S,7S,7aS)-7-benzoyl-4a,6,7a-trihydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)hexahydro-3,6-methanocyclopenta[c]pyran-1(3H)-one
InChIKey: UTKCEZMWSNDCMR-SAKMHLFVSA-N
SMILES: O=C1[C@]2([C@@](O)(C[C@@]([H])(O1)C3)[C@H]([C@@]3([C@@H]2C(C4=CC=CC=C4)=O)O)C(O5)=CC(OC)=CC5=O)O
Biological Activity: Deoxyenterocin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibiotic, antiviral, and antioxidant properties. It inhibits the growth of S. lutea, S. aureus, K. pneumoniae, and V. percolans in vitro when used at a concentration of 500 μg/mL. Deoxyenterocin (50 μg/mL) inhibits the cytopathic effect of influenza A H1N1 virus by 60.6% in vitro. It also prevents hydrogen peroxide-induced decreases in glutathione (GSH) levels and in the mitochondrial membrane potential in mouse primary cortical neuronal cultures when used at a concentration of 1 μM.
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Deoxyenterocin | Deoxyenterocin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibiotic, antiviral, and antioxidant properties. It inhibits the growth of S. lutea, S. aureus, K. pneumoniae, and V. percolans in vitro when used at a concentration of 500 μg/mL. Deoxyenterocin (50 μg/mL) inhibits the cytopathic effect of influenza A H1N1 virus by 60.6% in vitro. It also prevents hydrogen peroxide-induced decreases in glutathione (GSH) levels and in the mitochondrial membrane potential in mouse primary cortical neuronal cultures when used at a concentration of 1 μM. | |||||||||||||||||||||
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Keywords
