1090785-30-0
Chemical Structure
E17110
- CAS No.: 1090785-30-0
- Formula:C16H15FN2O5
- Molecular Weight:334.30
IUPAC Name: 1-oxo-1-(2-oxoimidazolidin-1-yl)propan-2-yl 5-fluoro-3-methylbenzofuran-2-carboxylate
InChIKey: MVSDPJNCAUPGBR-UHFFFAOYSA-N
SMILES: O=C(NCC1)N1C(C(C)OC(C2=C(C)C3=CC(F)=CC=C3O2)=O)=O
Biological Activity: E17110 is a liver X receptor β (LXRβ) agonist with an EC50 of 0.72 μM. E17110 can increase the expression of ATP-binding cassette transporter A1 (ABCA1) and G1 (ABCG1) in RAW264.7 macrophages. E17110 also reduce cellular lipid accumulation and promoted cholesterol efflux. E17110 can be used for the research of cardiovascular disease, such as atherosclerosis[1].
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E17110 | E17110 is a liver X receptor β (LXRβ) agonist with an EC50 of 0.72 μM. E17110 can increase the expression of ATP-binding cassette transporter A1 (ABCA1) and G1 (ABCG1) in RAW264.7 macrophages. E17110 also reduce cellular lipid accumulation and promoted cholesterol efflux. E17110 can be used for the research of cardiovascular disease, such as atherosclerosis. | |||||||||||||||||||||
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Keywords
