109292-91-3
Chemical Structure
N 0840
Synonym(s): N6-Cyclopentyl-9-methyladenine
- CAS No.: 109292-91-3
- Formula:C11H15N5
- Molecular Weight:217.27
InChIKey: LZMRVYPPUVMKOI-UHFFFAOYSA-N
SMILES: CN1C=NC2=C1N=CN=C2NC3CCCC3
Biological Activity: N 0840 is a neutral antagonist of adenosine A1 receptor (A1AR), with a Ki value of 279 nM in rats and 1185 nM in humans. N 0840 modulates adenosine A1 receptor to increase forskolin-induced cyclic 3′,5′-adenosine monophosphate production, with a GTP shift value close to 1. N 0840 can be used in studies of neuroprotection, cardiovascular/renal function[1].
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N 0840 | N 0840 is a neutral antagonist of adenosine A1 receptor (A1AR), with a Ki value of 279 nM in rats and 1185 nM in humans. N 0840 modulates adenosine A1 receptor to increase forskolin-induced cyclic 3′,5′-adenosine monophosphate production, with a GTP shift value close to 1. N 0840 can be used in studies of neuroprotection, cardiovascular/renal function. | |||||||||||||||||||||
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Keywords