111495-90-0
111495-90-0
Chemical Structure
3′-Azido-2′,3′-dideoxy-5-hydroxyuridine
- CAS No.: 111495-90-0
- Formula:C9H11N5O5
- Molecular Weight:269.21
IUPAC Name: 1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dione
InChIKey: AXXNSKSOBHVEGQ-UBKIQSJTSA-N
SMILES: OC[C@@H]1[C@@H](N=[N+]=[N-])C[C@H](N(C(N2)=O)C=C(O)C2=O)O1
Biological Activity: 3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3′-Azido-2′,3′-dideoxy-5-hydroxyuridine | 3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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