1119503-63-7

JNc-440 Chemical Structure
1119503-63-7

Chemical Structure

JNc-440

  • CAS No.: 1119503-63-7
  • Formula:C26H24N4O3
  • Molecular Weight:440.50

IUPAC Name: N-(3-(2,2-diphenylacetamido)propyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide

InChIKey: VMRVWMQQRPXUQU-UHFFFAOYSA-N

SMILES: O=C(C(N1)=NC2=C(C=CC=C2)C1=O)NCCCNC(C(C3=CC=CC=C3)C4=CC=CC=C4)=O

Biological Activity: JNc-440 is a potent antihypertensive agent. JNc-440 can enhance the interaction of TRPV4 and Ca2+-activated potassium channel 3 (KCa2.3) in endothelial cells. JNc-440 can also enhance vasodilation, and exerted antihypertensive effects in mice[1].

Cat. No. Product Name Purity Description Pricing
HY-120514
JNc-440 98.04% JNc-440 is a potent antihypertensive agent. JNc-440 can enhance the interaction of TRPV4 and Ca2+-activated potassium channel 3 (KCa2.3) in endothelial cells. JNc-440 can also enhance vasodilation, and exerted antihypertensive effects in mice.
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