112808-99-8
112808-99-8
Chemical Structure
CGS 18320B
- CAS No.: 112808-99-8
- Formula:C22H18N4O4
- Molecular Weight:402.40
InChIKey: ODDSIIZLFDPJQG-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(C(N2C=NC=C2)C3=CC=C(C=C3)C#N)C=C1.O=C(CCC(O)=O)O
Biological Activity: CGS 18320B is a human placental microsomal aromatase inhibitor with a Ki of 0.16 nM. CGS 18320B interacts reversibly with the enzyme's active site to block estrogen biosynthesis from androstenedione. CGS 18320B can be used for the research of aromatase inhibition and estrogen biosynthesis regulation[1].
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CGS 18320B | CGS 18320B is a human placental microsomal aromatase inhibitor with a Ki of 0.16 nM. CGS 18320B interacts reversibly with the enzyme's active site to block estrogen biosynthesis from androstenedione. CGS 18320B can be used for the research of aromatase inhibition and estrogen biosynthesis regulation. | |||||||||||||||||||||
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References
Keywords
