1144075-36-4
1144075-36-4
Chemical Structure
mTOR inhibitor-10
- CAS No.: 1144075-36-4
- Formula:C21H22FN5O2S
- Molecular Weight:427.50
InChIKey: RRNFUKFNHGBQEF-UHFFFAOYSA-N
SMILES: O=C(NCCF)NC1=CC=C(C2=NC3=C(C(N4CC5OC(CC5)C4)=N2)SC=C3)C=C1
Biological Activity: mTOR inhibitor-10 (Compound 9c) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 0.7 and 825 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 87 nM[1].
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mTOR inhibitor-10 | mTOR inhibitor-10 (Compound 9c) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 0.7 and 825 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 87 nM. | |||||||||||||||||||||
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