mTOR inhibitor-10
mTOR inhibitor-10 (Compound 9c) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 0.7 and 825 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 87 nM.
For research use only. We do not sell to patients.
- CAS No.: 1144075-36-4
- Formula: C21H22FN5O2S
- Molecular Weight:427.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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mTOR 0.7 nM (IC50) |
PI3Kα 825 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LNCaP | IC50 |
87 nM
Compound: 9c
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Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
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[PMID: 19897362] |
Chemical Information
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CAS No. 1144075-36-4
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Molecular Weight 427.50
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Formula C21H22FN5O2S
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SMILES
O=C(NCCF)NC1=CC=C(C2=NC3=C(C(N4CC5OC(CC5)C4)=N2)SC=C3)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
mTOR inhibitor-10 Related Classifications
HY-162023 Related Classifications
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