1144075-40-0
1144075-40-0
Chemical Structure
mTOR inhibitor-17
- CAS No.: 1144075-40-0
- Formula:C22H23N5O2S
- Molecular Weight:421.52
InChIKey: HBZPGFLLAMADHT-UHFFFAOYSA-N
SMILES: O=C(NC1CC1)NC2=CC=C(C3=NC4=C(C(N5CC6OC(CC6)C5)=N3)SC=C4)C=C2
Biological Activity: mTOR inhibitor-17 (Compound 9e) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 0.68 and 1359 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 40 nM[1].
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mTOR inhibitor-17 | mTOR inhibitor-17 (Compound 9e) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 0.68 and 1359 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 40 nM. | |||||||||||||||||||||
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