mTOR inhibitor-17
mTOR inhibitor-17 (Compound 9e) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 0.68 and 1359 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 40 nM.
For research use only. We do not sell to patients.
- CAS No.: 1144075-40-0
- Formula: C22H23N5O2S
- Molecular Weight:421.52
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
mTOR 0.68 nM (IC50) |
PI3Kα 1359 nM (IC50) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| LNCaP | IC50 |
40 nM
Compound: 9e
|
Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
|
[PMID: 19897362] |
Chemical Information
-
CAS No. 1144075-40-0
-
Molecular Weight 421.52
-
Formula C22H23N5O2S
-
SMILES
O=C(NC1CC1)NC2=CC=C(C3=NC4=C(C(N5CC6OC(CC6)C5)=N3)SC=C4)C=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
mTOR inhibitor-17 Related Classifications
HY-162025 Related Classifications
Powered by Bioz