mTOR inhibitor-17
mTOR inhibitor-17 (Compound 9e) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 0.68 and 1359 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 40 nM.
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- CAS. Nr.: 1144075-40-0
- Formel: C22H23N5O2S
- Molecular Weight:421.52
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
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mTOR 0.68 nM (IC50) |
PI3Kα 1359 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LNCaP | IC50 |
40 nM
Compound: 9e
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Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
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[PMID: 19897362] |
Chemical Information
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CAS. Nr. 1144075-40-0
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Molecular Weight 421.52
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Formel C22H23N5O2S
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SMILES
O=C(NC1CC1)NC2=CC=C(C3=NC4=C(C(N5CC6OC(CC6)C5)=N3)SC=C4)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
mTOR inhibitor-17 Related Classifications
HY-162025 Related Classifications
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