1144075-42-2
1144075-42-2
Chemical Structure
mTOR inhibitor-16
- CAS No.: 1144075-42-2
- Formula:C25H23N5O2S
- Molecular Weight:457.55
InChIKey: VROHDVQPMGULKN-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C2=NC3=C(C(N4CC5OC(CC5)C4)=N2)SC=C3)C=C1)NC6=CC=CC=C6
Biological Activity: mTOR inhibitor-16 (Compound 9f) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 1.25 and 82 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 140 nM[1].
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mTOR inhibitor-16 | mTOR inhibitor-16 (Compound 9f) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 1.25 and 82 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 140 nM. | |||||||||||||||||||||
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