1144075-44-4
Chemical Structure
mTOR inhibitor-13
- CAS No.: 1144075-44-4
- Formula:C24H22N6O2S
- Molecular Weight:458.54
InChIKey: IKYYAFMKEGKZGC-KDURUIRLSA-N
SMILES: O=C(NC1=CC=C(C2=NC3=C(C(N4C[C@@H]5O[C@@H](CC5)C4)=N2)SC=C3)C=C1)NC6=CC=CN=C6
Biological Activity: mTOR inhibitor-13 (compound 9g), an aryl ureido compound, is a potent and selective mTOR inhibitor with an IC50 of 0.29 nM. mTOR inhibitor-13 also inhibits PI3K-α with an IC50 of 119 nM[1].
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mTOR inhibitor-13 | mTOR inhibitor-13 (compound 9g), an aryl ureido compound, is a potent and selective mTOR inhibitor with an IC50 of 0.29 nM. mTOR inhibitor-13 also inhibits PI3K-α with an IC50 of 119 nM. | |||||||||||||||||||||
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Keywords