mTOR inhibitor-13
mTOR inhibitor-13 (compound 9g), an aryl ureido compound, is a potent and selective mTOR inhibitor with an IC50 of 0.29 nM. mTOR inhibitor-13 also inhibits PI3K-α with an IC50 of 119 nM.
For research use only. We do not sell to patients.
- CAS No.: 1144075-44-4
- Formula: C24H22N6O2S
- Molecular Weight:458.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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mTOR 0.29 nM (IC50) |
PI3Kα 119 nM (IC50) |
Chemical Information
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CAS No. 1144075-44-4
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Molecular Weight 458.54
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Formula C24H22N6O2S
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SMILES
O=C(NC1=CC=C(C2=NC3=C(C(N4C[C@@H]5O[C@@H](CC5)C4)=N2)SC=C3)C=C1)NC6=CC=CN=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)