116277-75-9
116277-75-9
Chemical Structure
Sodium gualenate hydrate
Synonym(s): Guaiazulenesulfonate sodium hydrate
- CAS No.: 116277-75-9
- Formula:C15H19NaO4S
- Molecular Weight:318.36
IUPAC Name: sodium 5-isopropyl-3,8-dimethylazulene-1-sulfonate hydrate
InChIKey: MBPDRKMZHLMXCP-UHFFFAOYSA-M
SMILES: O=S(C1=C2C(C)=CC=C(C(C)C)C=C2C(C)=C1)(O[Na])=O.O
Biological Activity: Sodium gualenate hydrate (Guaiazulenesulfonate sodium hydrate) is a derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis[1][2].
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Sodium gualenate hydrate | Sodium gualenate hydrate (Guaiazulenesulfonate sodium hydrate) is a derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis. | |||||||||||||||||||||
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References
- [1]. Nakamichi K, et al. Stabilization of sodium guaiazulene sulfonate in granules for tableting prepared using a twin-screw extruder. Eur J Pharm Biopharm. 2003 Nov;56(3):347-54. [Content Brief]
- [2]. Cao T, et al. Synthesis and Biological Evaluation of 3, 8-dimethyl-5-isopropylazulene Derivatives as Anti-gastric Ulcer Agent. Chem Biol Drug Des. 2016 Aug;88(2):264-71. [Content Brief]
Keywords
