1190043-25-4
Chemical Structure
Gatifloxacin-d4
Synonym(s): AM-1155-d4; BMS-206584-d4; PD135432-d4
- CAS No.: 1190043-25-4
- Formula:C19H18D4FN3O4
- Molecular Weight:379.42
IUPAC Name: 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl-2,2,5,5-d4)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChIKey: XUBOMFCQGDBHNK-CNVQUGECSA-N
SMILES: FC1=CC2=C(C(OC)=C1N3C([2H])(C(NC([2H])(C3)[2H])C)[2H])N(C4CC4)C=C(C(O)=O)C2=O
Biological Activity: Gatifloxacin-d4 (AM-1155-d4) is the deuterium labeled Gatifloxacin (HY-10581). Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50 = 13.8 μg/mL for S. aureus topoisomerase IV) and E.coli DNA gyrase (IC50 = 0.109 μg/mL)[1]. Gatifloxacin can be used for the study of bacterial conjunctivitis in vivo.
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Gatifloxacin-d4 | Gatifloxacin-d4 (AM-1155-d4) is the deuterium labeled Gatifloxacin (HY-10581). Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50 = 13.8 μg/mL for S. aureus topoisomerase IV) and E.coli DNA gyrase (IC50 = 0.109 μg/mL). Gatifloxacin can be used for the study of bacterial conjunctivitis in vivo. | |||||||||||||||||||||
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Gatifloxacin (Standard) | ≥98% | Gatifloxacin (Standard) is the analytical standard of Gatifloxacin. This product is intended for research and analytical applications. Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50=0.109 μg/ml). Gatifloxacin can be used to treat bacterial conjunctivitis in vivo. | ||||||||||||||||||||
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Gatifloxacin | 99.69% | Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic that can cross the blood-brain barrier, with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50=0.109 μg/ml). Gatifloxacin can be used to treat bacterial conjunctivitis in vivo. | ||||||||||||||||||||
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