1197397-89-9
1197397-89-9
Chemical Structure
CBL0137 hydrochloride
Synonym(s): Curaxin-137 hydrochloride; CBL-C137 hydrochloride
- CAS No.: 1197397-89-9
- Formula:C21H25ClN2O2
- Molecular Weight:372.89
IUPAC Name: 1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) hydrochloride
InChIKey: IXRKBBVMDMKAEB-UHFFFAOYSA-N
SMILES: CC(NCCN1C2=C(C3=C1C=CC(C(C)=O)=C3)C=C(C(C)=O)C=C2)C.[H]Cl
Biological Activity: CBL0137 hydrochloride is an inhibitor of the histone chaperone, FACT. CBL0137 hydrochloride can also activate p53 and inhibits NF-κB with EC50s of 0.37 and 0.47 μM, respectively.
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CBL0137 hydrochloride | 99.72% | CBL0137 hydrochloride is an inhibitor of the histone chaperone, FACT. CBL0137 hydrochloride can also activate p53 and inhibits NF-κB with EC50s of 0.37 and 0.47 μM, respectively. | ||||||||||||||||||||
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Keywords
