1202575-67-4
Chemical Structure
DS-1558
- CAS No.: 1202575-67-4
- Formula:C21H21F3O4
- Molecular Weight:394.38
IUPAC Name: (S)-3-ethoxy-3-(4-(((R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)propanoic acid
InChIKey: YHLQVQKZDZYMIP-MOPGFXCFSA-N
SMILES: FC(F)(C1=C2C([C@@H](CC2)OC3=CC=C(C=C3)[C@@H](OCC)CC(O)=O)=CC=C1)F
Biological Activity: DS-1558 is an orally active small molecule G protein-coupled receptor 40 agonist. DS-1558 not only increases the glucose-stimulated insulin secretion by glucagon like peptide-1 (GLP-1) but also potentiated the maximum insulinogenic effects of GLP-1 after an intravenous glucose injection in normal Sprague Dawley rats. DS-1558 is promising for research of type 2 diabetes[1].
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DS-1558 | DS-1558 is an orally active small molecule G protein-coupled receptor 40 agonist. DS-1558 not only increases the glucose-stimulated insulin secretion by glucagon like peptide-1 (GLP-1) but also potentiated the maximum insulinogenic effects of GLP-1 after an intravenous glucose injection in normal Sprague Dawley rats. DS-1558 is promising for research of type 2 diabetes. | |||||||||||||||||||||
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