120293-93-8
Chemical Structure
Juvenile hormone B 3 (mixture of diastereomers)
Synonym(s): Juvenile hormone III bisepoxide; Juvenile hormone bisepoxide; JHB3
- CAS No.: 120293-93-8
- Formula:C16H26O4
- Molecular Weight:282.38
IUPAC Name: methyl (E)-5-((2S,3S)-3-(2-((R)-3,3-dimethyloxiran-2-yl)ethyl)-3-methyloxiran-2-yl)-3-methylpent-2-enoate
InChIKey: ZKZPJBPCLACUKB-ORLMQAGASA-N
SMILES: CC(C)(O1)[C@H]1CC[C@]2([C@@H](O2)CC/C(C)=C/C(OC)=O)C
Biological Activity: Juvenile hormone B 3 (Juvenile hormone III bisepoxide)(mixture of diastereomers) is a sesquiterpenoid hormone. Juvenile hormone B 3 can be isolated from corpus allatum (CA) of high dipterans like the fruitfly and Drosophila melanogaster. JHB3 has anti-metamorphic activity and induces Kr-h1 expression by directly interacting with juvenile hormone (JH) receptors (Met and Gce). Juvenile hormone B 3 can be used for insect lethality research[1][2].
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Juvenile hormone B 3 (mixture of diastereomers) | Juvenile hormone B 3 (Juvenile hormone III bisepoxide)(mixture of diastereomers) is a sesquiterpenoid hormone. Juvenile hormone B 3 can be isolated from corpus allatum (CA) of high dipterans like the fruitfly and Drosophila melanogaster. JHB3 has anti-metamorphic activity and induces Kr-h1 expression by directly interacting with juvenile hormone (JH) receptors (Met and Gce). Juvenile hormone B 3 can be used for insect lethality research. | |||||||||||||||||||||
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- [1]. Wen D, et al. Methyl farnesoate plays a dual role in regulating Drosophila metamorphosis. PLoS Genet. 2015 Mar 16;11(3):e1005038. [Content Brief]
- [2]. Harshman LG, et al. Bioassays of compounds with potential juvenoid activity on Drosophila melanogaster: juvenile hormone III, bisepoxide juvenile hormone III and methyl farnesoates. J Insect Physiol. 2010 Oct;56(10):1465-70. [Content Brief]
