121341-41-1
121341-41-1
Chemical Structure
hIAPP22–27
- CAS No.: 121341-41-1
- Formula:C30H47N7O8
- Molecular Weight:633.74
InChIKey: INZKWABEOBCYEL-HRBVALIDSA-N
SMILES: O=C(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)[C@H](CC(N)=O)N
Biological Activity: hIAPP22-27 is a hexapeptide corresponding to residues 22-27 of human islet amyloid polypeptide (hIAPP) and is the key amyloid core sequence of hIAPP. hIAPP22-27 can self-assemble under neutral pH conditions to form β-sheet-containing amyloid fibrils and is cytotoxic to pancreatic β cells. hIAPP22-27 can be used in research related to type 2 diabetes[1].
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hIAPP22–27 | hIAPP22-27 is a hexapeptide corresponding to residues 22-27 of human islet amyloid polypeptide (hIAPP) and is the key amyloid core sequence of hIAPP. hIAPP22-27 can self-assemble under neutral pH conditions to form β-sheet-containing amyloid fibrils and is cytotoxic to pancreatic β cells. hIAPP22-27 can be used in research related to type 2 diabetes. | |||||||||||||||||||||
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