1216461-18-5
Chemical Structure
(Rac)-Fosfomycin (benzylamine)-13C3
Synonym(s): MK-0955 (benzylamine)-13C3
- CAS No.: 1216461-18-5
- Formula:C713C3H16NO4P
- Molecular Weight:248.19
IUPAC Name: phenylmethanamine (3-(methyl-13C)oxiran-2-yl-2,3-13C2)phosphonate
InChIKey: YFOCHWJDRUXOIQ-BURVIEGVSA-N
SMILES: NCC1=CC=CC=C1.O=P(O)([13CH]2[13CH](O2)[13CH3])O
Biological Activity: (Rac)-Fosfomycin (benzylamine)-13C3 is the 13C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].
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(Rac)-Fosfomycin (benzylamine)-13C3 | (Rac)-Fosfomycin (benzylamine)-13C3 is the 13C labeled Fosfomycin. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. | |||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Falagas ME, et al. Fosfomycin. Clin Microbiol Rev. 2016 Apr. 29(2):321-47. [Content Brief]
- [3]. Dijkmans AC, et al. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31. 6(4):24. [Content Brief]
Keywords
