1217780-14-7
Chemical Structure
L-Thyroxine-13C6-1
Synonym(s): Levothyroxine-13C6-1;T4-13C6-1
- CAS No.: 1217780-14-7
- Formula:C913C6H11I4NO4
- Molecular Weight:782.83
IUPAC Name: (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy-1,2,3,4,5,6-13C6)-3,5-diiodophenyl)propanoic acid
InChIKey: XUIIKFGFIJCVMT-DOEZJOBUSA-N
SMILES: N[C@H](C(O)=O)CC1=CC(I)=C(O[13C]2=[13CH][13C](I)=[13C]([13C](I)=[13CH]2)O)C(I)=C1
Biological Activity: L-Thyroxine-13C6-1 (Levothyroxine-13C6-1; T4-13C6-1) is a 13C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[1][2].
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L-Thyroxine-13C6-1 | L-Thyroxine-13C6-1 (Levothyroxine-13C6-1; T4-13C6-1) is a 13C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4). | |||||||||||||||||||||
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L-Thyroxine (Standard) | 98.67% | L-Thyroxine (Standard) is the analytical standard of L-Thyroxine. This product is intended for research and analytical applications. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4). | ||||||||||||||||||||
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Levothyroxine-d3 | Levothyroxine-d3 is the deuterium labeled Levothyroxine. | |||||||||||||||||||||
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L-Thyroxine-13C9,15N | L-Thyroxine-13C9,15N is the 13C6 ans 15N labeled L-Thyroxine (HY-18341). | |||||||||||||||||||||
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L-Thyroxine-13C6 | L-Thyroxine-13C6 is the 13C labeled L-Thyroxine. L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4). | |||||||||||||||||||||
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Thyroxine hydrochloride-13C6 | Thyroxine hydrochloride-13C6 is the 13C-labeled L-Thyroxine. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4). | |||||||||||||||||||||
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L-Thyroxine | 98.43% | L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4). | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief]
- [2]. Arici M, et al. Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients. Endocr J. 2018 Mar 28;65(3):317-323. [Content Brief]
