1223-36-5
1223-36-5
Chemical Structure
Clofexamide
Synonym(s): ANP 246; Amichlophene; Chlofexamide
- CAS No.: 1223-36-5
- Formula:C14H21ClN2O2
- Molecular Weight:284.78
IUPAC Name: 2-(4-chlorophenoxy)-N-(2-(diethylamino)ethyl)acetamide
InChIKey: UORGKWWJEQDTGX-UHFFFAOYSA-N
SMILES: CCN(CC)CCNC(COC1=CC=C(Cl)C=C1)=O
Biological Activity: Clofexamide (ANP 246) is an orally active antidepressant agent, exhibiting analgesic and anti-inflammatory activity. Clofexamide can be used for the research of depression, inflammatory disorders, peptic ulcer[1][2].
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Clofexamide | Clofexamide (ANP 246) is an orally active antidepressant agent, exhibiting analgesic and anti-inflammatory activity. Clofexamide can be used for the research of depression, inflammatory disorders, peptic ulcer. | |||||||||||||||||||||
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References
- [1]. Kirkpatrick D, et al. Identification of an N-oxide as the major metabolite of the analgesic O-(diethylaminoethyl)-4-chlorobenzaldoxime hydrochloride in dogs. Xenobiotica. 1977 Dec;7(12):747-55. [Content Brief]
- [2]. Irino O, et al. Studies on absorption, biotransformation and excretion of drug. 1. Metabolites of clofexamide in rat. Chem Pharm Bull (Tokyo). 1972 Jan;20(1):47-55. [Content Brief]
