1239488-96-0
1239488-96-0
Chemical Structure
URAT1&XO inhibitor 2
- CAS No.: 1239488-96-0
- Formula:C14H12BrNO3
- Molecular Weight:322.15
InChIKey: FWPXBKAQCQNVFM-DTQAZKPQSA-N
SMILES: BrC(C=C1)=CC=C1C/C(C2=C(C=C(C=C2)O)O)=N\O
Biological Activity: URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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URAT1&XO inhibitor 2 | 98.69% | URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia. | ||||||||||||||||||||
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References
Keywords
