1240494-14-7
1240494-14-7
Chemical Structure
SX-576
- CAS No.: 1240494-14-7
- Formula:C20H15BF4N2O4S
- Molecular Weight:466.21
IUPAC Name: (2-(((5-((4-fluorophenyl)carbamoyl)pyridin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronic acid
InChIKey: AEDMWJARWOMJKQ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(F)C=C1)C2=CN=C(SCC3=CC(OC(F)(F)F)=CC=C3B(O)O)C=C2
Biological Activity: SX-576 is a CXCR1 and CXCR2 antagonist with IC50 values of 31 nM and 21 nM, respectively. SX-576 inhibits neutrophil infiltration in a rat model of pulmonary inflammation. SX-576 can be used in studies related to pulmonary inflammation[1].
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SX-576 | SX-576 is a CXCR1 and CXCR2 antagonist with IC50 values of 31 nM and 21 nM, respectively. SX-576 inhibits neutrophil infiltration in a rat model of pulmonary inflammation. SX-576 can be used in studies related to pulmonary inflammation. | |||||||||||||||||||||
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References
Keywords
