1246741-19-4
Chemical Structure
Cathepsin E substrate e
- CAS No.: 1246741-19-4
- Formula:C61H82N16O18
- Molecular Weight:1327.40
InChIKey: AAIWALLSVHKGAY-BRHSRUOZSA-N
SMILES: O=C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CC(C1=CC=C(C=C1O2)OC)=CC2=O)=O)C)=O)=O)CC3=CC=CC=C3)=O)CO)=O)CC(C)C)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](CCCNC(N)=N)C(N)=O)=O)CCCCNC5=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C5)=O)C)=O)CCC4
Biological Activity: Cathepsin E substrate e is a substrate of Cathepsin E. Cathepsin E substrate e was designed in such a way that due to the close proximity of a Mca-donor and a Dnp-acceptor, a near complete intramolecular quenching effect was achieved in its intact state. After the proteolytic cleavage of the hydrophobic motif of the peptide substrate, both Mca and Dnp would be further apart, resulting in bright fluorescence[1].
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Cathepsin E substrate e | Cathepsin E substrate e is a substrate of Cathepsin E. Cathepsin E substrate e was designed in such a way that due to the close proximity of a Mca-donor and a Dnp-acceptor, a near complete intramolecular quenching effect was achieved in its intact state. After the proteolytic cleavage of the hydrophobic motif of the peptide substrate, both Mca and Dnp would be further apart, resulting in bright fluorescence. | |||||||||||||||||||||
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Keywords
