1246833-02-2
1246833-02-2
Chemical Structure
Teludipine-d6
- CAS No.: 1246833-02-2
- Formula:C28H32D6N2O6
- Molecular Weight:504.65
IUPAC Name: diethyl (E)-2-((bis(methyl-d3)amino)methyl)-4-(2-(3-(tert-butoxy)-3-oxoprop-1-en-1-yl)phenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey: DKLVJXTUCNPMDC-JKAPMHMVSA-N
SMILES: C(OCC)(=O)C=1C(C(C(OCC)=O)=C(C)NC1CN(C([2H])([2H])[2H])C([2H])([2H])[2H])C2=C(C=CC(OC(C)(C)C)=O)C=CC=C2
Biological Activity: Teludipine-d6 is the deuterium labeled Teludipine hydrochloride. Teludipine is a lipophilic calcium channel blocker[1][2].
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Teludipine-d6 | Teludipine-d6 is the deuterium labeled Teludipine hydrochloride. Teludipine is a lipophilic calcium channel blocker. | |||||||||||||||||||||
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Teludipine hydrochloride | Teludipine is a lipophilic calcium channel blocker. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Tolomeo M, et al. Effects of R-enantiomer (GR66234A) and L-enantiomer (GR66235A) of telupidine, a new dihydropyridine derivative, on cell lines displaying the multidrug resistant phenotype. Haematologica. 1994 Jul-Aug;79(4):328-33. [Content Brief]
