125652-47-3
Chemical Structure
CGP 31358
- CAS No.: 125652-47-3
- Formula:C19H19ClN4O2
- Molecular Weight:370.83
IUPAC Name: 1-(4-(2-(4-chlorophenyl)propan-2-yl)-2-methoxyphenyl)-1H-1,2,4-triazole-3-carboxamide
InChIKey: STTFFDLZKCMBQO-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C2=CC=C(C(C)(C3=CC=C(Cl)C=C3)C)C=C2OC)C=N1)N
Biological Activity: CGP 31358 is an anticonvulsant agent that binds to a site on the NMDA receptor complex that is coupled to both the transmitter recognition site and to the channel domain. CGP 31358 inhibits the binding of L-Glutamate to the NMDA receptor complex with an IC50 of 53 μM[1].
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CGP 31358 | CGP 31358 is an anticonvulsant agent that binds to a site on the NMDA receptor complex that is coupled to both the transmitter recognition site and to the channel domain. CGP 31358 inhibits the binding of L-Glutamate to the NMDA receptor complex with an IC50 of 53 μM. | |||||||||||||||||||||
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Keywords