1263409-34-2
Chemical Structure
AM432 sodium
- CAS No.: 1263409-34-2
- Formula:C29H31N2NaO5
- Molecular Weight:510.56
IUPAC Name: sodium 2-(4'-(6-ethoxypyridin-3-yl)-2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-[1,1'-biphenyl]-3-yl)acetate
InChIKey: KKQXNJWVSUWKOH-UHFFFAOYSA-M
SMILES: O=C(O[Na])CC1=CC(C2=CC=C(C3=CC=C(OCC)N=C3)C=C2CN(C(C4CC4)=O)CC)=C(OC)C=C1
Biological Activity: AM432 (sodium) is a potent and selective antagonist of the DP2 receptor (CRTH2). AM432 (sodium) exhibits excellent potency in a human whole blood eosinophil shape change assay with prolonged incubation. AM432 (sodium) also demonstrates excellent pharmacokinetics in dog and mouse models of inflammatory disease[1].
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AM432 sodium | AM432 (sodium) is a potent and selective antagonist of the DP2 receptor (CRTH2). AM432 (sodium) exhibits excellent potency in a human whole blood eosinophil shape change assay with prolonged incubation. AM432 (sodium) also demonstrates excellent pharmacokinetics in dog and mouse models of inflammatory disease. | |||||||||||||||||||||
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