12684-33-2
Chemical Structure
Sibiromycin
- CAS No.: 12684-33-2
- Formula:C24H33N3O7
- Molecular Weight:475.53
IUPAC Name: (11R,11aS)-7-(((2S,3R,4R,5S,6S)-3,4-dihydroxy-4,6-dimethyl-5-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-9,11-dihydroxy-8-methyl-2-((E)-prop-1-en-1-yl)-1,10,11,11a-tetrahydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one
InChIKey: RAGFPHFDFVNLCG-INYQBOQCSA-N
SMILES: O=C1C2=CC(O[C@H]3[C@@H]([C@](O)([C@H]([C@@H](O3)C)NC)C)O)=C(C)C(O)=C2N[C@@H]([C@@]4([H])N1C=C(C4)/C=C/C)O
Biological Activity: Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor groove at the NH2 of guanine[1][2].
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Sibiromycin | Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor groove at the NH2 of guanine. | |||||||||||||||||||||
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Keywords
