127481-29-2
Chemical Structure
L-674573
- CAS No.: 127481-29-2
- Formula:C28H27NO3S
- Molecular Weight:457.58
IUPAC Name: 2-((4-phenyl-1-(4-(quinolin-2-ylmethoxy)phenyl)butyl)thio)acetic acid
InChIKey: JOIXGLLMSDPZDN-UHFFFAOYSA-N
SMILES: O=C(CSC(CCCC1=CC=CC=C1)C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)O
Biological Activity: L-674573 is a quinoline leukotriene synthesis inhibitor, inhibiting Calcimycin (HY-N6687)- and N-Formyl-Met-Leu-Phe (HY-P0224)-induced leukotriene production with IC50s of 100 nM and 50 nM, respectively. L-674573 selectively inhibits Calcimycin- and N-Formyl-Met-Leu-Phe-induced 5-lipoxygenase translocation[1].
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L-674573 | 99.54% | L-674573 is a quinoline leukotriene synthesis inhibitor, inhibiting Calcimycin (HY-N6687)- and N-Formyl-Met-Leu-Phe (HY-P0224)-induced leukotriene production with IC50s of 100 nM and 50 nM, respectively. L-674573 selectively inhibits Calcimycin- and N-Formyl-Met-Leu-Phe-induced 5-lipoxygenase translocation. | ||||||||||||||||||||
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Keywords
