2. GPCR/G Protein
  3. Leukotriene Receptor
  4. L-674573

L-674573 is a quinoline leukotriene synthesis inhibitor that selectively inhibits 5-lipoxygenase translocation.

For research use only. We do not sell to patients.

L-674573 Chemical Structure

L-674573 Chemical Structure

CAS No. : 127481-29-2

Size Price Stock Quantity
5 mg USD 66 In-stock
10 mg USD 105 In-stock
25 mg USD 205 In-stock
50 mg USD 325 In-stock
100 mg USD 520 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

L-674573 is a quinoline leukotriene synthesis inhibitor that selectively inhibits 5-lipoxygenase translocation[1].

Molecular Weight

457.58

Formula

C28H27NO3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CSC(CCCC1=CC=CC=C1)C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (273.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1854 mL 10.9271 mL 21.8541 mL
5 mM 0.4371 mL 2.1854 mL 4.3708 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1854 mL 10.9271 mL 21.8541 mL 54.6353 mL
5 mM 0.4371 mL 2.1854 mL 4.3708 mL 10.9271 mL
10 mM 0.2185 mL 1.0927 mL 2.1854 mL 5.4635 mL
15 mM 0.1457 mL 0.7285 mL 1.4569 mL 3.6424 mL
20 mM 0.1093 mL 0.5464 mL 1.0927 mL 2.7318 mL
25 mM 0.0874 mL 0.4371 mL 0.8742 mL 2.1854 mL
30 mM 0.0728 mL 0.3642 mL 0.7285 mL 1.8212 mL
40 mM 0.0546 mL 0.2732 mL 0.5464 mL 1.3659 mL
50 mM 0.0437 mL 0.2185 mL 0.4371 mL 1.0927 mL
60 mM 0.0364 mL 0.1821 mL 0.3642 mL 0.9106 mL
80 mM 0.0273 mL 0.1366 mL 0.2732 mL 0.6829 mL
100 mM 0.0219 mL 0.1093 mL 0.2185 mL 0.5464 mL
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L-674573 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-674573127481-29-2L674573L 674573Leukotriene Receptorleukotriene synthesis5-lipoxygenase translocationInhibitorinhibitorinhibit

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