128022-68-4
128022-68-4
Chemical Structure
ADX-10061
Synonym(s): CEE 03-310; NNC 687
- CAS No.: 128022-68-4
- Formula:C19H20N2O4
- Molecular Weight:340.37
IUPAC Name: (S)-5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol
InChIKey: XZPSYCOYKJRHKE-MRXNPFEDSA-N
SMILES: OC1=C([N+]([O-])=O)C=C2CCN(C)C[C@H](C3=C(OCC4)C4=CC=C3)C2=C1
Biological Activity: ADX-10061 (compound NNC 687) is a dopamine D1 receptor antagonist with the Ki values of 9.1 nM, 5.8 nM, > 10 000 nM and 355 nM for adenylyl cyclase, D1, D2 and 5-HT2 receptor, respectively. ADX-10061 can be used for study of schizophrenia[1].
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ADX-10061 | ADX-10061 (compound NNC 687) is a dopamine D1 receptor antagonist with the Ki values of 9.1 nM, 5.8 nM, > 10 000 nM and 355 nM for adenylyl cyclase, D1, D2 and 5-HT2 receptor, respectively. ADX-10061 can be used for study of schizophrenia. | |||||||||||||||||||||
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References
Keywords
