128311-08-0
128311-08-0
Chemical Structure
(S)-PNU-282987 hydrochloride
- CAS. Nr.: 128311-08-0
- Formula:C14H18Cl2N2O
- Molecular Weight:301.21
IUPAC Name: (S)-4-chloro-N-(quinuclidin-3-yl)benzamide hydrochloride
InChIKey: HSEQUIRZHDYOIX-BTQNPOSSSA-N
SMILES: O=C(C1=CC=C(Cl)C=C1)N[C@H]2C3CCN(CC3)C2.Cl
Biological Activity: (S)-PNU-282987 hydrochloride is an isoform of PNU-282987 (HY-12560). PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems[1].
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(S)-PNU-282987 hydrochloride | (S)-PNU-282987 hydrochloride is an isoform of PNU-282987 (HY-12560). PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems. | |||||||||||||||||||||
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