1286694-67-4
Chemical Structure
Britannilactone diacetate
Synonym(s): 1,6-O,O-Diacetylbritannilactone; Di-O-acetylbritannilactone
- CAS No.: 1286694-67-4
- Formula:C19H26O6
- Molecular Weight:350.41
IUPAC Name: (S)-4-((3aR,4S,7aR)-4-acetoxy-6-methyl-3-methylene-2-oxo-2,3,3a,4,7,7a-hexahydrobenzofuran-5-yl)pentyl acetate
InChIKey: MVCCWTMPDBIKCJ-QMHBMSAFSA-N
SMILES: O=C1O[C@@]2([H])[C@@]([C@H](OC(C)=O)C([C@@H](C)CCCOC(C)=O)=C(C)C2)([H])C1=C
Biological Activity: Britannilactone diacetate (1,6-O,O-Diacetylbritannilactone; Compound 2) exhibits potential NO inhibition effect. Britannilactone diacetate exhibits activity against NO production induced by LPS in BV-2 microglial cells with the EC50 value of 6.3 μM. Britannilactone diacetate exhibits a favorable blood-brain barriers (BBB) penetration and absorption, distribution, metabolism, excretion, and toxicity (ADMET) property[1].
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Britannilactone diacetate | Britannilactone diacetate (1,6-O,O-Diacetylbritannilactone; Compound 2) exhibits potential NO inhibition effect. Britannilactone diacetate exhibits activity against NO production induced by LPS in BV-2 microglial cells with the EC50 value of 6.3 μM. Britannilactone diacetate exhibits a favorable blood-brain barriers (BBB) penetration and absorption, distribution, metabolism, excretion, and toxicity (ADMET) property. | |||||||||||||||||||||
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