129228-55-3
Chemical Structure
11-Dehydro thromboxane B3
Synonym(s): 11-Dehydro-TXB3
- CAS No.: 129228-55-3
- Formula:C20H30O6
- Molecular Weight:366.45
IUPAC Name: (Z)-7-((2R,3S,4S)-4-hydroxy-2-((S,1E,5Z)-3-hydroxyocta-1,5-dien-1-yl)-6-oxotetrahydro-2H-pyran-3-yl)hept-5-enoic acid
InChIKey: OAHMLWQISGEXBB-XMEKLSCHSA-N
SMILES: O[C@@H]1[C@@H]([C@H](OC(C1)=O)/C=C/[C@H](C/C=C\CC)O)C/C=C\CCCC(O)=O
Biological Activity: 11-Dehydro thromboxane B3 (11-Dehydro-TXB3) is a pro-inflammatory thromboxane lipid mediator that the body generates following administration of eicosapentaenoic acid. 11-Dehydro thromboxane B3 is an enzymatic metabolite of Thromboxane B3 (HY-113445) and also serves as a biomarker for Thromboxane A3 biosynthesis in humans in vivo. 11-Dehydro thromboxane B3 is used in metabolism-related research[1][2].
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11-Dehydro thromboxane B3 | 11-Dehydro thromboxane B3 (11-Dehydro-TXB3) is a pro-inflammatory thromboxane lipid mediator that the body generates following administration of eicosapentaenoic acid. 11-Dehydro thromboxane B3 is an enzymatic metabolite of Thromboxane B3 (HY-113445) and also serves as a biomarker for Thromboxane A3 biosynthesis in humans in vivo. 11-Dehydro thromboxane B3 is used in metabolism-related research. | |||||||||||||||||||||
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References
- [1]. Ikuta K, et al. Development of a multi-targeted metabolomics platform for semi-quantification of faecal metabolites: a proof-of-concept analysis in human faeces. Microbiome research reports. 2026;5(1):7. [Content Brief]
- [2]. Ishibashi M, et al. Identification of 11-dehydrothromboxane B3 in human urine after administration of eicosapentaenoic acid. Biomed Environ Mass Spectrom. 1990 Jun;19(6):387-9. [Content Brief]
