130641-36-0
Chemical Structure
Picumeterol
Synonym(s): GR114297A
- CAS No.: 130641-36-0
- Formula:C21H29Cl2N3O2
- Molecular Weight:426.38
IUPAC Name: (R)-1-(4-amino-3,5-dichlorophenyl)-2-((6-(2-(pyridin-2-yl)ethoxy)hexyl)amino)ethan-1-ol
InChIKey: NUBLQEKABJXICM-FQEVSTJZSA-N
SMILES: O[C@H](C1=CC(Cl)=C(C(Cl)=C1)N)CNCCCCCCOCCC2=CC=CC=N2
Biological Activity: Picumeterol (GR114297A) is a potent and selective β2-adrenoceptor agonist with bronchodilator and anti-bronchoconstrictor effects. Picumeterol produces long-lasting relaxation of airways smooth muscle both in vitro and in vivo. Picumeterol is cleared from plasma through a rapid and extensive hepatic metabolism. Picumeterol is proming for rasearch of asthma and related diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Picumeterol | Picumeterol (GR114297A) is a potent and selective β2-adrenoceptor agonist with bronchodilator and anti-bronchoconstrictor effects. Picumeterol produces long-lasting relaxation of airways smooth muscle both in vitro and in vivo. Picumeterol is cleared from plasma through a rapid and extensive hepatic metabolism. Picumeterol is proming for rasearch of asthma and related diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Weersink EJ, et al. Picumeterol: dissociation of improvement in lung function and reduction of airways hyperresponsiveness in asthmatics. Br J Clin Pharmacol. 1997 Feb;43(2):169-76. [Content Brief]
- [2]. Barrow A, et al. Kinetics and disposition of picumeterol in animals. Xenobiotica. 1995 Sep;25(9):993-1007. [Content Brief]
