132928-46-2
132928-46-2
Chemical Structure
PF-10040
- CAS No.: 132928-46-2
- Formula:C20H24ClNO2
- Molecular Weight:345.86
IUPAC Name: 1-(3,4-dimethoxyphenethyl)-6-methyl-3,4-dihydroisoquinoline hydrochloride
InChIKey: FJHOALINTTUIKP-UHFFFAOYSA-N
SMILES: COC1=C(OC)C=CC(CCC2=NCCC3=CC(C)=CC=C23)=C1.Cl
Biological Activity: PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].
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PF-10040 | PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis. | |||||||||||||||||||||
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References
- [1]. Herd CM, et, al. Effect of PF 10040 on PAF-induced airway responses in neonatally immunized rabbits. Br J Pharmacol. 1994 Jan;111(1):7-12. [Content Brief]
- [2]. Wallace JL, et, al. Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF. J Lipid Mediat. 1993 Jun;7(2):183-96. [Content Brief]
Keywords
