1329563-41-8
Chemical Structure
Guaifenesin-d5
- No. CAS: 1329563-41-8
- Formula:C10H9D5O4
- Molecular Weight:203.25
IUPAC Name: 3-(2-methoxyphenoxy)propane-1,1,2,3,3-d5-1,2-diol
InChIKey: HSRJKNPTNIJEKV-RORPNYJOSA-N
SMILES: O(C(C(C(O)([2H])[2H])(O)[2H])([2H])[2H])C1=C(OC)C=CC=C1
Biological Activity: Guaifenesin-d5 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. Guaifenesin also has narcotic effect[1][2].
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Guaifenesin-d5 | Guaifenesin-d5 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. Guaifenesin also has narcotic effect. | |||||||||||||||||||||
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Guaifenesin (Standard) | 99.65% | Guaifenesin (Standard) is the analytical standard of Guaifenesin. This product is intended for research and analytical applications. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. | ||||||||||||||||||||
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Guaifenesin-d3 | 99.00% | Guaifenesin-d3 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. | ||||||||||||||||||||
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Guaifenesin | 99.86% | Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. | ||||||||||||||||||||
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-
Similarity Score 0.91
HY-W412326Guaietolin -
Similarity Score 0.89
HY-B1283Mephenesin -
Similarity Score 0.84
HY-W0170913-Phenoxy-1,2-propanediol -
Similarity Score 0.83
HY-N3263Methyleugenolglycol -
Similarity Score 0.81
HY-1078472-(2-Methoxyphenoxy)ethylamine hydrochloride -
Similarity Score 0.81
HY-A0133Chlorphenesin -
Similarity Score 0.79
HY-N136844-(4-Hydroxy-3-methoxyphenyl)butane-1,2-diol -
Similarity Score 0.78
HY-W131158Tamsulosin impurity 15 -
Similarity Score 0.77
HY-W016487Ranolazine impurity 10 -
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Bennett, S., N. Hoffman, and M. Monga, Ephedrine- and guaifenesin-induced nephrolithiasis. J Altern Complement Med, 2004. 10(6): p. 967-9. [Content Brief]
