13396-93-5
13396-93-5
Chemical Structure
Des-N-methylnoracronycine
- CAS. Nr.: 13396-93-5
- Formula:C18H15NO3
- Molecular Weight:293.32
InChIKey: RPWNPBFZWFWZNJ-UHFFFAOYSA-N
SMILES: O=C1C2=C(NC3=C4C=CC(C)(C)OC4=CC(O)=C13)C=CC=C2
Biological Activity: Des-N-methylnoracronycine is an acridone alkaloid found in the root bark of Glycosmis pentaphylla (Retz.) Correa. Des-N-methylnoracronycine has antitumor and platelet aggregation inhibitory activities[1][2][3][4].
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Des-N-methylnoracronycine | Des-N-methylnoracronycine is an acridone alkaloid found in the root bark of Glycosmis pentaphylla (Retz.) Correa. Des-N-methylnoracronycine has antitumor and platelet aggregation inhibitory activities. | |||||||||||||||||||||
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References
- [1]. Govindachari T R, et al. Alkaloids of Glycosmis pentaphylla (Retz.) correa. Tetrahedron, 1966, 22(10): 3245-3252.
- [2]. Kawaii S, et al. The antiproliferative effect of acridone alkaloids on several cancer cell lines. J Nat Prod. 1999 Apr;62(4):587-9. [Content Brief]
- [3]. Kawaii S, et al. Acridones as inducers of HL-60 cell differentiation. Leuk Res. 1999 Mar;23(3):263-9. [Content Brief]
- [4]. Leu YL, et al. Antiplatelet aggregation principles from Glycosmis citrifolia. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives. 1998;12(S1):S77-9.
