1345853-49-7
1345853-49-7
Chemical Structure
Dynamin IN-2
- CAS No.: 1345853-49-7
- Formula:C22H21ClN2O
- Molecular Weight:364.87
IUPAC Name: 1-(9H-carbazol-9-yl)-3-((4-chlorobenzyl)amino)propan-2-ol
InChIKey: AEKXFKTYWDQZGU-UHFFFAOYSA-N
SMILES: ClC(C=C1)=CC=C1CNCC(CN2C3=CC=CC=C3C4=CC=CC=C42)O
Biological Activity: Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM[1].
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Dynamin IN-2 | 98.93% | Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM. | ||||||||||||||||||||
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