1346242-31-6
1346242-31-6
Chemical Structure
Rivastigmine carbamate impurity
Synonym(s): 3-Nitrophenyl ethyl(methyl)carbamate
- CAS No.: 1346242-31-6
- Formula:C10H12N2O4
- Molecular Weight:224.21
IUPAC Name: 3-nitrophenyl ethyl(methyl)carbamate
InChIKey: DFECCKHSYUWCIJ-UHFFFAOYSA-N
SMILES: O=C(OC1=CC=CC([N+]([O-])=O)=C1)N(CC)C
Biological Activity: Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is an impurity of Rivastigmine. Rivastigmine is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM, 4.15 μM, respectively[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Rivastigmine carbamate impurity | 99.98% | Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is an impurity of Rivastigmine. Rivastigmine is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM, 4.15 μM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Ziwei Chen, et al. Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease. Eur J Med Chem. 2017 Jan 5;125:784-792. [Content Brief]
- [2]. Qian-Sheng Yu, et al. Anticholinesterase activity of compounds related to geneserine tautomers. N-Oxides and 1,2-oxazines. J Med Chem. 2002 Aug 15;45(17):3684-91. [Content Brief]
Keywords
