1351522-05-8
1351522-05-8
Chemical Structure
AC710 Mesylate
- CAS No.: 1351522-05-8
- Formula:C32H46N6O7S
- Molecular Weight:658.81
IUPAC Name: N-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-5-((1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxy)picolinamide methanesulfonate
InChIKey: AUMMSMBRVDYUME-UHFFFAOYSA-N
SMILES: O=C(C1=NC=C(OC2CC(C)(C)N(CC)C(C)(C)C2)C=C1)NC3=CC=C(NC(NC4=NOC(C(C)(C)C)=C4)=O)C=C3.CS(=O)(O)=O
Biological Activity: AC710 Mesylate is a potent PDGFR inhibitor with Kds of 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ, respectively.
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AC710 Mesylate | AC710 Mesylate is a potent PDGFR inhibitor with Kds of 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ, respectively. | |||||||||||||||||||||
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