1356355-11-7
Chemical Structure
Saquinavir-d9
Synonym(s): Ro 31-8959-d9
- CAS No.: 1356355-11-7
- Formula:C38H41D9N6O5
- Molecular Weight:679.90
IUPAC Name: (S)-N1-((2S,3R)-3-hydroxy-4-((3S,4aS,8aS)-3-((2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)carbamoyl)octahydroisoquinolin-2(1H)-yl)-1-phenylbutan-2-yl)-2-(quinoline-2-carboxamido)succinamide
InChIKey: QWAXKHKRTORLEM-ABBOPLMISA-N
SMILES: C([C@H]([C@H](CC1=CC=CC=C1)NC([C@@H](NC(=O)C2=NC3=C(C=C2)C=CC=C3)CC(N)=O)=O)O)N4[C@H](C(NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)C[C@]5([C@@](C4)(CCCC5)[H])[H]
Biological Activity: Saquinavir-d9 (Ro 31-8959-d9) is the deuterium labeled Saquinavir (HY-17007). Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Saquinavir-d9 | Saquinavir-d9 (Ro 31-8959-d9) is the deuterium labeled Saquinavir (HY-17007). Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Saquinavir (Standard) | ≥98% | Saquinavir (Standard) (Ro 31-8959 (Standard)) is the analytical standard of Saquinavir (HY-17007). This product is intended for research and analytical applications. Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Saquinavir-13C6 | Saquinavir-13C6 (Ro 31-8959-13C6) is 13C labeled Saquinavir (HY-17007). Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Saquinavir | 99.77% | Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Pettoello-Mantovani M, et al. Saquinavir-mediated inhibition of human immunodeficiency virus (HIV) infection in SCID mice implanted with human fetal thymus and liver tissue: an in vivo model for evaluating the effect of drug therapy on HIV infection in lymphoid tissues. Antimicrob Agents Chemother. 1997 Sep;41(9):1880-7. [Content Brief]
