135662-06-5
Chemical Structure
Dnp-PYAYWMR
- CAS No.: 135662-06-5
- Formula:C54H65N13O14S
- Molecular Weight:1152.24
InChIKey: HHLUMDBUTRSUFV-LTJWQYCVSA-N
SMILES: N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CCSC)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](C)NC([C@H](CC4=CC=C(O)C=C4)NC([C@H]5N(C6=CC=C([N+]([O-])=O)C=C6[N+]([O-])=O)CCC5)=O)=O)=O)=O)=O)=O
Biological Activity: Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1].
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Dnp-PYAYWMR | Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm. | |||||||||||||||||||||
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Keywords
